Anemia can be classified into following types:

1. Production versus destruction or loss
The kinetic approach gives the most relevant classification of anemia. This approach focuses on the evaluation of several hematological parameters for example, the blood reticulocyte count. This then classifies the defects concerned with decreased RBC production as well as its increased destruction and loss. Clinical signs of destruction of RBCs show hemolysis in the blood smear. Increased level of LDH suggests increased loss of blood cells.

2. Red blood cell size
The morphological approach classifies anemia on the basis of size of RBCs. This can be done either automatically or by analyzing the peripheral blood smear. The size of red blood cells is reflected in terms of mean corpuscular volume (MCV). If the size of cell is less than 80 fl then anemia is said to be microcytic and if it is 80-100 fl then anemia is normocytic. If the size of cell is more than 100 fl then anemia is classified as macrocytic. This approach quickly gives some idea about the cause of anemia for example microcytic anemia is the result of iron deficiency. The peripheral blood smear often gives an idea about the white blood cells. Abnormal picture of white blood cells projects towards a defect in the bone marrow.

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